Lamp2b信号肽

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August undefined, 2024

http://www.biofeng.com/adjy/zhili/pcDNA%20GNSTM-3-RVG-10-Lamp2b-HA.html Tīmeklis2024. gada 27. sept. · LAMP-2 Antibody (H4B4) is an IgG 1 κ mouse monoclonal LAMP-2 antibody (also designated LAMP2 antibody, LAMPB antibody or lysosomal …

工程化外泌体——药物递送专家&外泌体研究利器 - 知乎

TīmeklisThe fusion protein HuR-Lamp2b and Lamp2b-HuR were detected in the exosomes derived from HuRLamp2b and Lamp2b-HuR-transfected cells ( Supplementary Figure 1), suggesting that both Lamp2b fusion ... TīmeklisLOCUS pcDNA Flag Lamp2b-HA 6880 bp ds-DNA circular SYN 06-AUG-2024 DEFINITION Flag tag with 3 residue spacer fused to the N-terminus of Lamp2b, a transmembrane exosomal protein. 3 residue spacer then HA tag fused to the C-terminus of Lamp2b.. ACCESSION . VERSION . KEYWORDS pcDNA Flag Lamp2b-HA … it is needless to say that

信号肽与新生肽链的运输和加工（一） - 知乎 - 知乎专栏

Tīmeklis2024. gada 24. dec. · LAMP-2B is the predominant LAMP-2 isoform expressed in human CMs. ( A) Expression of the three LAMP-2 isoforms in different types of cells was examined by RNA-seq or qPCR. RNAs from three human hearts were used for qPCR. FPKM, fragments per kilobase of exon per million reads. ( B) Immunoblotting … Tīmeklis2015. gada 27. marts · Indeed, peptides fused to the N terminus of exosome-associated transmembrane protein Lamp2b were cleaved in samples derived from both cells and exosomes. To suppress peptide loss, we engineered targeting peptide-Lamp2b fusion proteins to include a glycosylation motif at various positions. Introduction of this … TīmeklisLAMP2 (D5C2P) Rabbit mAb 可识别 LAMP2 总蛋白的内源水平。物种反应性：人来源/纯化使用人 LAMP2 蛋白氨基端特异的重组蛋白对动物进行免疫接种来产生单克隆 … neighborhood medical center orange avenue

pcDNA GNSTM-3-RVG-10-Lamp2b-HA - biofeng.com

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Tīmeklis2024. gada 8. janv. · Remarkably, LAMP-2B functions independently of syntaxin 17 (STX17), a protein that is essential for autophagosome-lysosome fusion in non-CMs. … Tīmeklis一种基于Lamp2b的融合蛋白可用于在表面显示狂犬病病毒糖蛋白（RVG），当这些胞外体被系统地给予时，表面展示的RVG导致这些胞外体在小鼠的神经元和大脑中积聚 … neighborhood medical center beltlineTīmeklisAll lanes : Anti-LAMP2B antibody - Lysosome Marker (ab18529) at 1 µg/ml Lane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : HEK293 (Human) Whole Cell Lysate Lysates/proteins at 20 µg per lane. Secondary All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed at 1/50000 dilution Developed using … neighborhood medical clinic

"Tīmeklis使用人 LAMP2 蛋白氨基端特异的重组蛋白对动物进行免疫接种来产生单克隆抗体。背景溶酶体相关膜蛋白 1 和 2（LAMP1 和 LAMP2）是两种含量丰富的溶酶体膜蛋白 (1,2)。两者都是跨膜蛋白，并且在溶酶体的内腔面氨基末端被高度糖基化，这能保护蛋白质不被水解 (3)。 LAMP1 蛋白羧基末端暴露在细胞浆中，同时它含有一个将 LAMP 蛋白靶 … " - Lamp2b信号肽

Lamp2b信号肽

LAMP-2B regulates human cardiomyocyte function by mediating …

TīmeklisSynthetic peptide corresponding to Human LAMP2B aa 350 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin. LAMP2 has 3 distinct isoforms, … Tīmeklis2024. gada 21. marts · LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include Danon Disease and Left Ventricular Noncompaction.Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System.Gene Ontology (GO) annotations …

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Tīmeklis2024. gada 1. febr. · The pEGFP-C1-RVG-Lamp2b expressing vector was kindly provided by Prof. Matthew J A Wood’ lab from University of Oxford [70]. DNA sequence encoding the glycosylation sequon (GNSTM), E7 Peptide [55] and a glycine-serine spacer were synthesized and subcloned to replace the RVG fragment by XhoI/BspeI … Tīmeklis2024. gada 24. apr. · 是引导新合成的蛋白质向分泌通路转移的短（长度5-30个氨基酸）肽链。常指新合成多肽链中用于指导蛋白质的跨膜转移（定位）的n-末端的氨基酸序列（有时不一定在n端）。

Tīmeklis名称： BPSV40-NLS. 描述：A classical nuclear localization signal (NLS) consists of two clusters of basic residues separated by 10–12 residues (bipartite), NLS … Tīmeklis2024. gada 15. nov. · 细胞外小囊泡（ sEVs RVG ）的脑部神经特异性靶向是通过将 s EVs膜蛋白lamp2b 和神经靶向性的狂犬病毒糖蛋白衍生肽（RVG）融合递呈在 …

TīmeklisReceive email alerts when new plasmids with this gene become available. Log in to subscribe to Addgene Alerts. Description lysosomal associated membrane protein 2. Also known as CD107b, DND, LAMP-2, LAMPB, LGP-96, LGP110. Species Homo sapiens. Entrez ID 3920. MGC ID BC002965. TīmeklisLAMP-2 Antibody (H4B4) is an IgG 1 κ mouse monoclonal LAMP-2 antibody (also designated LAMP2 antibody, LAMPB antibody or lysosomal associated membrane …

Tīmeklis2024. gada 24. nov. · Lamp2b-HuR融合蛋白功能化的外泌体能够将被RNA结合基序识别的RNA靶标驱动至溶酶体以在受体细胞中降解。该系统在富含溶酶体的巨噬细胞中 …

Tīmeklis2024. gada 5. jūl. · 信号肽捕获系统 (signal sequence trap, SST) 就是依据分泌性蛋白质的这一特性进行基因克隆的功能性基因克隆系统 , 由 Tashiro K 等于 1993 年建立, 该方法可以快速、大量地克隆真核细胞编码分泌性蛋白的基因序列, 目前用该系统已经获得了大量编码分泌性蛋白的基因 [4]。 SST 法包括两个基本步骤: ( 1) 构建并转染和报告基 … neighborhood medical center havana flLysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins. The protein encoded by this gene is a member of a family of membrane glycoproteins. This … Skatīt vairāk The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b. When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C … Skatīt vairāk Lysosomes are cell organelles found in most animal cells. Their main functions center around breaking down materials and debris in the cell. Some of this is done via acid hydrolases that degrade foreign materials and have specialized autolytic functions. These … Skatīt vairāk • CA77.1 • QX39 Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. Skatīt vairāk LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of cancerous tumors, specifically in cells of highly metastatic cancer such as colon cancer and melanoma. They are rarely found on … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information … Skatīt vairāk it is neither possible nor usefulTīmeklisLAMP2具有三种同工型：LAMP2A，LAMP2B和LAMP2C，其中LAMP2B是在心肌细胞中表达的主要同工型。腺相关病毒（adeno-associated virus，AAV）是目前发现的一 … it is need to 使い方