Webbdoustnie. Multimedia w Wikimedia Commons. Talidomid – organiczny związek chemiczny zbudowany z reszty ftalimidowej i glutarimidowej, stosowany jako lek o działaniu przeciwwymiotnym, przeciwbólowym, usypiającym i hipnotycznym. Talidomid został uzyskany przez chemików z Chemie Grünenthal z Republiki Federalnej Niemiec w 1953 … WebbIt is an anti-emetic drug and is used to treat morning sickness in pregnant women. Thalidomide is also used to treat leprosy, multiple myeloma, Crohn′s disease and human …
Clinical pharmacology of thalidomide - PubMed
Webb30 juli 2009 · Binding of pomalidomide and other thalidomide-related drugs changes the substrate specificity of the human protein, leading to decreased degradation of MEIS2 and other target proteins and increased degradation of MYC, IRF4, IKZF1 and IKZF3. Gene Name: CRBN Uniprot ID: Q96SW2 Molecular Weight: 50545.375 Da References WebbThalidomide was a drug sold in more than 40 countries, mainly in Europe, in the early 1960s as a sleeping aid and to pregnant women as an antiemetic (a drug that prevents vomiting) to combat morning sickness. shoe brands that offer arch support
Enantiomers: Thalidomide and Ibuprofen – Learning in Parallel
Webb28 apr. 2012 · A reversal back to the ketone results in a mix of (R) and (S) enantiomers. In the body, this tautomerization is generally catalyzed by basic amino acids. Specifically, albumin is the main catalyst in humans. While this is beyond the scope of your question, the reason that only (S)-thalidomide causes birth defects is that it can insert itself ... WebbThalidomide: the tragedy of birth defects and the effective treatment of disease. Thalidomide was a widely used drug in the late 1950s and early 1960s for the treatment … WebbThalidomide is a pharmaceutical drug, first prepared in 1957 in Germany, prescribed for treating morning sickness in pregnant women. The drug was discovered to be … racehorse slipway